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HRT Even Worse Than Previous Found
2003-08-08 23:33:59
Now that the one million woman study in UK has calculated its data, HRT has
been found wanting again. Pempro doubles the risk of breast cancer, while estogen alone raises the risk about 30%. It is utterly amazing how treatments become standard with self-selection as the basis for decision-making. Once again too much medical care kills.
2003-08-09 11:53:47
>Subject: HRT Even Worse Than Previous Found >From: georgeconklin@earthlink.net >study in UK has calculated its data, HRT has >been found wanting again. Pempro doubles the risk of breast cancer, while >estogen alone raises the risk about 30%. It is utterly amazing how >treatments become standard with self-selection as the basis for >decision-making. Once again too much medical care kills. Once again, a MAN that knows little about health care drops one of his pearls of wisdom. Denise
2003-08-09 12:12:50
"DWood78828" news:20030809075347.10408.00002096@mb-m05.aol.com... > >Subject: HRT Even Worse Than Previous Found > >From: georgeconklin@earthlink.net > > >study in UK has calculated its data, HRT has > >been found wanting again. Pempro doubles the risk of breast cancer, > >estogen alone raises the risk about 30%. It is utterly amazing how > >treatments become standard with self-selection as the basis for > > >decision-making. Once again too much medical care kills. > > Once again, a MAN that knows little about health care drops one of his > of wisdom. > I thought he was correct and there are some REAL issues regarding hormone replacement? It was all over the networks. > Denise >
2003-08-09 22:17:30
DWood78828 news:20030809075347.10408.00002096@mb-m05.aol.com... > >Subject: HRT Even Worse Than Previous Found > >From: georgeconklin@earthlink.net > > >study in UK has calculated its data, HRT has > >been found wanting again. Pempro doubles the risk of breast cancer, > >estogen alone raises the risk about 30%. It is utterly amazing how > >treatments become standard with self-selection as the basis for > > >decision-making. Once again too much medical care kills. > > Once again, a MAN that knows little about health care drops one of his > of wisdom. > > Denise > >
2003-08-09 22:18:17
Karl > > "DWood78828" > news:20030809075347.10408.00002096@mb-m05.aol.com... > > >Subject: HRT Even Worse Than Previous Found > > >From: georgeconklin@earthlink.net > > > > >study in UK has calculated its data, HRT has > > >been found wanting again. Pempro doubles the risk of breast cancer, > while > > >estogen alone raises the risk about 30%. It is utterly amazing how > > >treatments become standard with self-selection as the basis for > > > > >decision-making. Once again too much medical care kills. > > > > Once again, a MAN that knows little about health care drops one of his > pearls > > of wisdom. > > > > I thought he was correct and there are some REAL issues regarding hormone > replacement? > It was all over the networks. > > > Denise > > > > > at research and want to go on with harmful medical customs is really shocking.
2003-08-09 22:19:47
Larry news:tlbajvsp2jt8knvdjvejgt76t8ci7382nh@4ax.com... > Denise, > > I agree that George is a dolt with regard to health care issues...but > what does his gender have to do with anything? > > Are you saying that "a man" isn't capable of understanding research > surrounding HRT, or that being a woman gives one a better > understanding of the literature? > > LT > Both of you are into the money machine, not health care.
2003-08-10 00:42:31
"Karl" > > "DWood78828" > news:20030809075347.10408.00002096@mb-m05.aol.com... > > >Subject: HRT Even Worse Than Previous Found > > >From: georgeconklin@earthlink.net > > > > >study in UK has calculated its data, HRT has > > >been found wanting again. Pempro doubles the risk of breast cancer, > while > > >estogen alone raises the risk about 30%. It is utterly amazing how > > >treatments become standard with self-selection as the basis for > > > > >decision-making. Once again too much medical care kills. > > > > Once again, a MAN that knows little about health care drops one of his > pearls > > of wisdom. > > > > I thought he was correct and there are some REAL issues regarding hormone > replacement? > It was all over the networks. > > > Denise There are major changes underway with regards to prescribing hormone replacement medications. I have discussed this before, but will summarize by saying that although the Women's Health Initiative trial had a number of design flaws (every study has some flaws), data from that trial suggest that HRT leads to an increased risk of breast cancer, heart disease (mostly within the first year of use), certain blood clots, and stroke. It appears to decrease the incidence of colon cancer and osteoporosis and clearly reduces hot flushes and vaginal dryness. For the purists out there, the major issues with the WHI trial is that is really was not a primary prevention trial. Many of the "healthy" women had conditions that may predispose to cardiac disease, such as obesity and hypertension, and the average age HRT was started was 63. Physicians don't prescribe HRT often to women who are 63; we prescribe it to women just starting menopause, which on average is age 51. Monkey research has shown that estrogen seems to prevent atherosclerosis but will not remove it after it develops. So, perhaps HRT would prevent heart disease if given at, say, age 50 but not at 63, or perhaps the WHI was correct and HRT does not prevent heart disease at all. Unfortunately, I doubt anyone will conduct the study that would answer that question, which is a true primary prevention trial which starts HRT at age 50 and follows patients over time until the conclusion of the study. In addition, it appears likely that HRT leads to an increase in breast cancer that increases with the duration of use. Cardiac disease is about 10 times more common than breast cancer, so "we" thought that the reduction in heart disease would offset the small increase in breast cancer. Again, it would take a different study to prove this, but the best we have is a huge, randomized trial that suggests we should not use HRT for cardiac disease prevention. To put the WHI in perspective, it showed a 24% increase in cardiac disease. That sounds like a lot, until you realize that out of 10,000 controls there were something like 33 cases of heart disease per year. That's an increase of 24%, which actually was about an additional 7/10,000 cases, for a total of 39 out of 10,000. If you were one of those 7 women, that's a bad thing, but 7 out of 10,000 is not an enormous number. To put this in perspective, the absolute risk of a car accident in the US is about 800 per 10,000 people per year. Hopefully absolute numbers like this will help put HRT into perspective. I prescribe a number of medications with more risks than HRT. However, many of the conditions HRT treats, such as hot flushes, may be amenable to non-medical treatment. Obviously one would want to try proven non-medical treatment as long as it appears safe. I discuss HRT with my patients, just as I discuss other medications. I do not prescribe HRT to prevent or treat heart disease, and I suggest that patients who want to use HRT limit it to 1-3 years, if possible, because the risk of breast cancer increases with time. Most patients with severe hot flushes that are not amenable to non-medical therapy want HRT. Hopefully they will be able to wean from it within a reasonable time period. Ashley D. Ashley Hill, MD
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